The big thing with Acrylic tank is that they do scratch a lot easier than glass, and you need to be careful when cleaning them, especially towards the bottom, as you don't want to pick up any sand. You can also scratch them with rocks, so you do need to be more careful if you have one. I've been using these mesh bags, which fit around the magnets, Aflie told me about them, and they're very good in not picking up the sand, plus the mesh isn't completely flat around the acrylic panel as it the case when you use the pads on the magnets, so if a piece of sand is caught in it, it's less likely to scratch the panel.
The weight issue and leaking, especially living in the city, was one of the major reasons that I went with acrylic on my large fish tanks, as I didn't want to have any issues with the tanks leaking.