To some extent this answer may depend on what you are keeping in the tank. Some corals may benefit from unnaturally high organics, and residual inorganics if they also rise, and some might be hurt by them. Hobbyists evidence suggests this to be the case.
The case of plankton is more complicated, IMO. I've seen no studies that showed whether there is much living plankton in typical reef tanks, and whether such plankton is removed by skimming. Moreover, once you start skimming, even very gently, you might deplete plankton, and even more extensive skimming might do little or nothing to the near zero plankton levels.